Rabbit Anti-Human MAGEL2 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9UJ55 |
| Gene Symbols | MAGEL2 |
| Protein Name / Synonyms | MAGEL2 (C-term) |
| Clonality | Polyclonal |
| Preparation | This MAGEL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499-529 amino acids from the C-terminal region of human MAGEL2. |
| Concentration (lot specific) | 0.350 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGE is unknown, may play a role in embryonal development and tumor transformation or aspects of tumor progression.
Specificity
Other Names
MAGEL2; NDNL1; MAGE-like protein 2; Necdin-like protein 1; Protein nM15
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
58669
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | MAGEL2 Antibody (D514) (Cat# 102-16666) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the MAGEL2 antibody detected the MAGEL2 protein (arrow). |
 | MAGEL2 Antibody (C-term) (Cat# 102-16666)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MAGEL2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.