Rabbit Anti-Human MAPK1 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P28482 |
| Gene Id | 5594 |
| Gene Symbols | MAPK1 |
| Protein Name / Synonyms | MAPK1 (C-term) |
| Clonality | Polyclonal |
| Preparation | This MAPK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-285 amino acids from the C-terminal region of human MAPK1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Cardiovascular Disease, Cancer, MAPK Signaling |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
ERK2 is a member of the MAP kinase subfamily of Ser/Thr protein kinases. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine
Other Names
MAPK1; ERK2; PRKM1; PRKM2; Mitogen-activated protein kinase 1; ERT1; Extracellular signal-regulated kinase 2; MAP kinase isoform p42; Mitogen-activated protein kinase 2
NCBI Accession #
NP_002736.3;NP_620407.1
Other Accession #
P63086; P63085; P46196
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
41390
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of anti-ERK2 C-term Pab (Cat# 102-17389) in UV-treated HL-60 cell lysate. ERK2 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. |
 | Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with ERK2 antibody (C-term) (Cat# 102-17389), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.