Rabbit Anti-Human MARK3 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P27448 |
| Gene Id | 4140 |
| Gene Symbols | MARK3 |
| Protein Name / Synonyms | MARK3 (C-term) |
| Clonality | Polyclonal |
| Preparation | This MARK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 570-601 amino acids from the C-terminal region of human MARK3. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | IHC-P, Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
MARK proteins are involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2, and MAP4. MARK3 was originally identified as a marker that was induced by treatment with DNA damaging agents, and loss of MARK3 was found with carcinogenesis in the pancreas. MARK3 may be involved in cell cycle regulation, and alterations in the MARK3 gene may lead to carcinogenesis.
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
MARK3; CTAK1; EMK2; MAP/microtubule affinity-regulating kinase 3; C-TAK1; Cdc25C-associated protein kinase 1; ELKL motif kinase 2; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Serine/threonine-protein kinase p78
NCBI Accession #
NP_001122390.1;NP_001122391.1;NP_001122392.1;NP_001122393.1;NP_002367.4
Other Accession #
Q8VHF0; Q03141
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
84489
Recommended Dilutions
IHC: 1:50-100; WB: 1:1000
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
 | MARK3 Antibody (S569) (Cat# 102-17198) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the MARK3 antibody detected the MARK3 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.