Rabbit Anti-Human MNDA (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P41218 |
| Gene Id | 4332 |
| Gene Symbols | MNDA |
| Protein Name / Synonyms | MNDA (N-term) |
| Clonality | Polyclonal |
| Preparation | This MNDA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-53 amino acids from the N-terminal region of human MNDA. |
| Concentration (lot specific) | 0.260 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.
Specificity
Other Names
MNDA; Myeloid cell nuclear differentiation antigen
NCBI Accession #
NP_002423.1
Other Accession #
NP_002423.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
45836
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | Western blot analysis of MNDA Antibody (N-term) Pab (Cat# 102-11009) pre-incubated without(lane 1) and with(lane 2) blocking peptide in CEM cell line lysate. MNDA Antibody (N-term) (arrow) was detected using the purified Pab. |
 | MNDA Antibody (N-term) (Cat# 102-11009)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MNDA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | MNDA Antibody (N-term) (Cat# 102-11009) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.