Rabbit Anti-Human Myostatin (GDF8) (N-term) Antibody, 200 µl
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Product Description
Specifications
| Size | 200 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O14793 |
| Gene Id | 2660 |
| Gene Symbols | MSTN |
| Protein Name / Synonyms | Myostatin (GDF8) (N-term) |
| Clonality | Polyclonal |
| Preparation | This Myostatin (GDF8) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-38 amino acids from the N-terminal region of human Myostatin (GDF8). |
| Concentration (lot specific) | 2.000 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
GDF8 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.
Specificity
Predicted Reactivity
Bovine, Pig, Monkey
Other Names
MSTN; GDF8; Growth/differentiation factor 8; Myostatin
NCBI Accession #
NP_005250.1
Other Accession #
O18831; Q95J86; O18836
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
42750
Recommended Dilutions
WB: 1:1000; IHC: 1:50
 | Western blot analysis of anti-GDF8 N-term Pab (Cat# 102-14963) in mouse liver tissue lysate. GDF8 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. |
 | Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with GDF8 antibody (N-term )(Cat# 102-14963), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.