Rabbit Anti-Human NM23 (NME1) (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P15531 |
| Gene Id | 4830 |
| Gene Symbols | NME1 |
| Protein Name / Synonyms | NM23 (NME1) (N-term) |
| Clonality | Polyclonal |
| Preparation | This NM23 (NME1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human NM23 (NME1). |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IF, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
NME1 was identified because of its reduced mRNA transcript levels in highly metastatic cells. NME1 encodes the 'A' isoform of nucleoside diphosphate kinase (NDK). NDK exists as a hexamer composed of the 'A' (NME1) and 'B' (encoded by NME2) isoforms. Mutations in NME1 have been identified in aggressive neuroblastomas.
Specificity
Other Names
NME1; NDPKA; NM23; Nucleoside diphosphate kinase A; Granzyme A-activated DNase; Metastasis inhibition factor nm23; Tumor metastatic process-associated protein; nm23-H1
NCBI Accession #
NP_000260.1;NP_937818.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
17149
Recommended Dilutions
WB: 1:1000; IF: 1:10-50; IHC: 1:50-100
 | NME1 Antibody (F40) (Cat# 102-17789) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the NME1 antibody detected the NME1 protein (arrow). |
 | Confocal immunofluorescent analysis of NM23 (NME1) Antibody (N-term)(Cat# 102-17789) with A375 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.