Rabbit Anti-Human NR3C1 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P04150 |
| Gene Id | 2908 |
| Gene Symbols | NR3C1 |
| Protein Name / Synonyms | NR3C1 (C-term) |
| Clonality | Polyclonal |
| Preparation | This NR3C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 713-742 amino acids from the C-terminal region of human NR3C1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, IF |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance.
Specificity
Other Names
Nuclear receptor subfamily 3 group C member 1; Glucocorticoid receptor, GR,GRL, NR3C1
NCBI Accession #
NP_000167.1;NP_001018084.1;NP_001018085.1;NP_001018086.1;NP_001018087.1;NP_001018661.1;NP_001019265.1;NP_001191187.1;NP_001191188.1;NP_001191189.1;NP_001191190.1;NP_001191191.1;NP_001191192.1;NP_00119
Other Accession #
P04150-2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
85659
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; IF: 1:10-50
 | Western blot analysis of NR3C1 Antibody (C-term) (Cat# 102-15778) in A549 cell line lysates (35ug/lane). NR3C1 (arrow) was detected using the purified Pab. |
 | NR3C1 Antibody (C-term) (Cat# 102-15778) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NR3C1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | Confocal immunofluorescent analysis of NR3C1 Antibody (C-term)(Cat# 102-15778) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.