Rabbit Anti-Human OCT3/4 (C279) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q01860 |
| Gene Id | 5460 |
| Gene Symbols | POU5F1 |
| Protein Name / Synonyms | OCT3/4 (C279) |
| Clonality | Polyclonal |
| Preparation | This OCT3/4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-297 amino acids from human OCT3/4. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
Specificity
Other Names
POU5F1; OCT3; OCT4; OTF3; POU domain, class 5, transcription factor 1; Octamer-binding protein 3; Octamer-binding protein 4; Octamer-binding transcription factor 3
NCBI Accession #
NP_002692.2
Other Accession #
Q06416; NP_002692.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
38571
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | OCT3/4 Antibody (C279) (Cat# 102-11139) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the OCT3/4 antibody detected the OCT3/4 protein (arrow). |
 | OCT3/4 Antibody (C279) (Cat# 102-11139)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OCT3/4 Antibody (C279) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.