Rabbit Anti-Human PCPTP1 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q15256 |
| Gene Id | 5801 |
| Gene Symbols | PTPRR |
| Protein Name / Synonyms | PCPTP1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This PCPTP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-265 amino acids from the N-terminal region of human PCPTP1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
PCPTP1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene for this protein predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of the gene for this protein was reported to be regulated by the nerve growth factor, which suggested a function in neuronal growth and differentiation.
Specificity
Other Names
PTPRR; ECPTP; PTPRQ; Receptor-type tyrosine-protein phosphatase R; Ch-1PTPase; NC-PTPCOM1; Protein-tyrosine phosphatase PCPTP1
NCBI Accession #
NP_001193944.1;NP_001193945.1;NP_002840.2;NP_570897.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
73834
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | The anti-PCPTP1 Pab (Cat# 102-17859) is used in Western blot to detect PCPTP1 in placenta tissue lysate. |
 | Formalin-fixed and paraffin-embedded human brain tissue reacted with hPCPTP1-Y249, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.