Rabbit Anti-Human PDGFRL (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q15198 |
| Gene Id | 5157 |
| Gene Symbols | PDGFRL |
| Protein Name / Synonyms | PDGFRL (C-term) |
| Clonality | Polyclonal |
| Preparation | This PDGFRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-357 amino acids from the C-terminal region of human PDGFRL. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
PDGFRL bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL may function as a tumor suppressor.
Specificity
Other Names
PDGFRL; PRLTS; Platelet-derived growth factor receptor-like protein; PDGF receptor beta-like tumor suppressor
NCBI Accession #
NP_006198.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
41861
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of anti-PDGFRL Antibody (C-term)(Cat# 102-17538) in Hela cell line lysates (35ug/lane).PDGFRL(arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human colon carcinoma reacted with PDGFRL antibody (C-term) (Cat# 102-17538), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
 | Western blot analysis of PDGFRL (arrow) using rabbit polyclonal PDGFRL-T343 (Cat# 102-17538). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PDGFRL gene. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.