Rabbit Anti-Human Phospho-ATRIP(S239) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q8WXE1 |
| Gene Id | 84126 |
| Gene Symbols | ATRIP |
| Protein Name / Synonyms | Phospho-ATRIP(S239) |
| Clonality | Polyclonal |
| Preparation | This ATRIP Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S239 of human ATRIP. |
| Concentration (lot specific) | 0.360 mg/ml |
| Recommended Applications | Dot Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.
Specificity
Predicted Reactivity
Monkey
Other Names
ATRIP; AGS1; ATR-interacting protein; ATM and Rad3-related-interacting protein
NCBI Accession #
NP_001257951.1;NP_001257952.1;NP_115542.2;NP_569055.1
Other Accession #
Q9N077; NP_115542.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
85838
Recommended Dilutions
DB: 1:500
 | Dot blot analysis of Phospho-ATRIP-S239 Antibody Phospho-specific Pab (Cat# 102-12767) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.