Rabbit Anti-Human Phospho-bcl-2(S70) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P10415 |
| Gene Id | 596 |
| Gene Symbols | BCL2 |
| Protein Name / Synonyms | Phospho-bcl-2(S70) |
| Clonality | Polyclonal |
| Preparation | This bcl-2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S70 of human bcl-2. |
| Concentration (lot specific) | 0.350 mg/ml |
| Recommended Applications | Western Blotting, Dot Blotting |
| Research Area | Apoptosis, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq].
Specificity
Other Names
BCL2; Apoptosis regulator Bcl-2
NCBI Accession #
NP_000624.2
Other Accession #
NP_000624.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
26266
Recommended Dilutions
DB: 1:500; WB: 1:1000
 | Dot blot analysis of Phospho-bcl-2-S70 Antibody Phospho-specific Pab (Cat# 102-15649) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml. |
 | Western blot analysis of extracts from Jurkat cells,untreated or treated with paclitaxel,using phospho-Bcl2(Ser70)(left) or Bcl2 antibody(right). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.