Rabbit Anti-Human Phospho-PARP1(S274) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P09874 |
| Gene Id | 142 |
| Gene Symbols | PARP1 |
| Protein Name / Synonyms | Phospho-PARP1(S274) |
| Clonality | Polyclonal |
| Preparation | This PARP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S274 of human PARP1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Dot Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Specificity
Other Names
PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; ADP-ribosyltransferase diphtheria toxin-like 1; NAD(+) ADP-ribosyltransferase 1; Poly[ADP-ribose] synthase 1
NCBI Accession #
NP_001609.2
Other Accession #
NP_001609.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
113084
Recommended Dilutions
DB: 1:500
 | Dot blot analysis of Phospho-PARP1-S274 Antibody Phospho-specific Pab (Cat# 102-15630) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.