Rabbit Anti-Human Phospho-TEK(Y1113) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q02763 |
| Gene Id | 7010 |
| Gene Symbols | TEK |
| Protein Name / Synonyms | Phospho-TEK(Y1113) |
| Clonality | Polyclonal |
| Preparation | This TEK Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1113 of human TEK. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Dot Blotting |
| Research Area | Angiogenesis, Cardiovascular Disease, Cancer, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
Specificity
Predicted Reactivity
Mouse, Zebrafish, Bovine
Other Names
TEK;TIE2,;VMCM,;VMCM1;Angiopoietin-1 receptor; Endothelial tyrosine kinase; Tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains-2; Tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor TIE-2, hTIE2; p140 TEK; CD_antigen=CD202b
NCBI Accession #
NP_000450.2
Other Accession #
Q02858; O73791; Q06807
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
125830
Recommended Dilutions
DB: 1:500
 | Dot blot analysis of anti-Phospho-TEK-pY1113 Antibody (Cat# 102-15476) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.