Rabbit Anti-Human PI3KCG (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P48736 |
| Gene Id | 5294 |
| Gene Symbols | PIK3CG |
| Protein Name / Synonyms | PI3KCG (C-term) |
| Clonality | Polyclonal |
| Preparation | This PI3KCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1074-1102 amino acids from the C-terminal region of human PI3KCG. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Angiogenesis, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
PI3KCG belongs to the pi3/pi4-kinase family of proteins. This protein is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells.
Specificity
Predicted Reactivity
Mouse, Pig
Other Names
PIK3CG; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; Phosphoinositide-3-kinase catalytic gamma polypeptide; Serine/threonine protein kinase PIK3CG; p120-PI3K
NCBI Accession #
NP_001269355.1;NP_001269356.1;NP_002640.2
Other Accession #
O02697; Q9JHG7; NP_002640
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
126454
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of PI3KCG Antibody (C-term) (Cat# 102-17762) in K562 cell line lysates (35ug/lane). PI3KCG (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.