Rabbit Anti-Human PITRM1 (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q5JRX3 |
| Gene Id | 10531 |
| Gene Symbols | PITRM1 |
| Protein Name / Synonyms | PITRM1 (Center) |
| Clonality | Polyclonal |
| Preparation | This PITRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-518 amino acids from the Central region of human PITRM1. |
| Concentration (lot specific) | 0.260 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.
Specificity
Other Names
PITRM1; KIAA1104; MP1; Presequence protease, mitochondrial; Pitrilysin metalloproteinase 1
NCBI Accession #
NP_001229236.1;NP_001229238.1;NP_055704.2
Other Accession #
NP_055704.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
117413
Recommended Dilutions
WB: 1:1000
 | PITRM1 Antibody (Center) (Cat# 102-11540) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PITRM1 antibody detected the PITRM1 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.