Rabbit Anti-Human PKM2 (C-term C474) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P14618 |
| Gene Id | 5315 |
| Gene Symbols | PKM |
| Protein Name / Synonyms | PKM2 (C-term C474) |
| Clonality | Polyclonal |
| Preparation | This PKM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 460-489 amino acids from the C-terminal region of human PKM2. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Angiogenesis |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
Specificity
Predicted Reactivity
Rabbit
Other Names
PKM; OIP3; PK2; PK3; PKM2; Pyruvate kinase isozymes M1/M2; Cytosolic thyroid hormone-binding protein; Opa-interacting protein 3; Pyruvate kinase 2/3; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; Tumor M2-PK; p58
NCBI Accession #
NP_001193725.1;NP_001193726.1;NP_001193727.1;NP_001193728.1;NP_002645.3;NP_872270.1;NP_872271.1
Other Accession #
P11974
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
57937
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of anti-PKM2 Antibody (C-term C474)(Cat# 102-17161) in CEM cell line lysates (35ug/lane). PKM2(arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with PKM2 antibody (C-term C474) (Cat# 102-17161), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.