Rabbit Anti-Human PREX1 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q8TCU6 |
| Gene Id | 57580 |
| Gene Symbols | PREX1 |
| Protein Name / Synonyms | PREX1 (C-term) |
| Clonality | Polyclonal |
| Preparation | This PREX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1134-1163 amino acids from the C-terminal region of human PREX1. |
| Concentration (lot specific) | 0.420 mg/ml |
| Recommended Applications | FC, IHC-P, Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.
Specificity
Other Names
PREX1; KIAA1415; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
NCBI Accession #
NP_065871.2
Other Accession #
NP_065871.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
186203
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
 | PREX1 Antibody (C-term) (Cat# 102-11637) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the PREX1 antibody detected the PREX1 protein (arrow). |
 | PREX1 Antibody (C-term) (Cat# 102-11637)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PREX1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | PREX1 Antibody (C-term) (Cat# 102-11637) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.