Rabbit Anti-Human PTPN18 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q99952 |
| Gene Id | 26469 |
| Gene Symbols | PTPN18 |
| Protein Name / Synonyms | PTPN18 (C-term) |
| Clonality | Polyclonal |
| Preparation | This PTPN18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 430-459 amino acids from the C-terminal region of human PTPN18. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Specificity
Predicted Reactivity
Mouse
Other Names
PTPN18; BDP1; Tyrosine-protein phosphatase non-receptor type 18; Brain-derived phosphatase
NCBI Accession #
NP_001135842.1;NP_055184.2
Other Accession #
Q61152; NP_055184.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
50482
Recommended Dilutions
WB: 1:1000
 | PTPN18 Antibody (C-term) (Cat# 102-13195) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PTPN18 antibody detected the PTPN18 protein (arrow). |
 | Western blot analysis of PTPN18 (arrow) using rabbit polyclonal PTPN18 Antibody (C-term) (Cat# 102-13195). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PTPN18 gene. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.