Rabbit Anti-Human PUM2 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q8TB72 |
| Gene Id | 23369 |
| Gene Symbols | PUM2 |
| Protein Name / Synonyms | PUM2 (N-term) |
| Clonality | Polyclonal |
| Preparation | This PUM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-162 amino acids from the N-terminal region of human PUM2. |
| Concentration (lot specific) | 0.35 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
PUM2 is a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. This protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of this protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation.
Specificity
Other Names
PUM2; KIAA0235; PUMH2; Pumilio homolog 2
NCBI Accession #
NP_056132.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
114216
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of PUM2 (arrow) using rabbit polyclonal PUM2 Antibody (N-term) (Cat# 102-17422). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PUM2 gene (Lane 2) (Origene Technologies). |
 | Formalin-fixed and paraffin-embedded human testis tissue reacted with PUM2 Antibody (C-term) (Cat# 102-17422), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.