Rabbit Anti-Human RACGAP1 (N-term)

Rabbit Anti-Human RACGAP1 (N-term) Antibody, 400 ul
$334.00
In stock
Code:
102-11106
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Product Description

Specifications

Size 400 µl
Protein Name / Synonyms RACGAP1 (N-term)
Accession Number Q9H0H5
Gene Symbols RACGAP1
Gene Id 29127
Concentration (lot specific) 0.260 mg/ml
Preparation This RACGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-50 amino acids from the N-terminal region of human RACGAP1.
Host Species Rabbit
Clonality Polyclonal
Species Human

Introduction

Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO (see MIM 165370), RAC (see RAC1; MIM 602048), and CDC42 (MIM 116952). GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.

Specificity

Other Names
RACGAP1; KIAA1478; MGCRACGAP; Rac GTPase-activating protein 1; Male germ cell RacGap; Protein CYK4 homolg
NCBI Accession #
NP_001119575.1;NP_001119576.1;NP_037409.2
Other Accession #
NP_001119575.1; NP_037409.2

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
71027
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; IF: 1:10-50; FC: 1:10-50
RACGAP1 Antibody (N-term) (Cat# 102-11106) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the RACGAP1 antibody detected the RACGAP1 protein (arrow).
RACGAP1 Antibody (N-term) (Cat# 102-11106)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RACGAP1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Confocal immunofluorescent analysis of RACGAP1 Antibody (N-term)(Cat# 102-11106) with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
RACGAP1 Antibody (N-term) (Cat# 102-11106) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
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