Rabbit Anti-Human RNH1 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P13489 |
| Gene Id | 6050 |
| Gene Symbols | RNH1 |
| Protein Name / Synonyms | RNH1 (C-term) |
| Clonality | Polyclonal |
| Preparation | This RNH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 425-454 amino acids from the C-terminal region of human RNH1. |
| Concentration (lot specific) | 0.350 mg/ml |
| Recommended Applications | Western Blotting, IF |
| Research Area | Angiogenesis |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.
Specificity
Other Names
RNH1; PRI; RNH; Ribonuclease inhibitor; Placental ribonuclease inhibitor; Ribonuclease/angiogenin inhibitor 1
NCBI Accession #
NP_002930.2;NP_976317.1;NP_976318.1;NP_976319.1;NP_976320.1;NP_976321.1;NP_976322.1;NP_976323.1
Other Accession #
NP_976318.1; NP_976317.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
49973
Recommended Dilutions
WB: 1:1000; IF: 1:10-50
 | Western blot analysis of lysate from HT29 cell line,using RNH1 Antibody (C-term)(Cat# 102-11564).102-11564 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug per lane. |
 | Confocal immunofluorescent analysis of RNH1 Antibody (C-term) (Cat# 102-11564) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.