Rabbit Anti-Human SETDB1 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q15047 |
| Gene Id | 9869 |
| Gene Symbols | SETDB1 |
| Protein Name / Synonyms | SETDB1 (C-term) |
| Clonality | Polyclonal |
| Preparation | This SETDB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1193-1225 amino acids from the C-terminal region of human SETDB1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su(var)3-9 and 'Enhancer of zeste' proteins, from which the acronym SET is derived. Studies have suggested that the SET domain may be a signature of proteins that modulate transcriptionally active or repressed chromatin states through chromatin remodeling activities.
Specificity
Predicted Reactivity
Mouse, Zebrafish, Xenopus
Other Names
SETDB1; KIAA0067; KMT1E; Histone-lysine N-methyltransferase SETDB1; ERG-associated protein with SET domain; Histone H3-K9 methyltransferase 4; Lysine N-methyltransferase 1E; SET domain bifurcated 1
NCBI Accession #
NP_001138887.1;NP_001230420.1;NP_036564.3
Other Accession #
Q08BR4; Q6INA9; O88974
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
143157
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of anti-SETDB1 Pab(Cat# 102-10782) in Ramos cell line lysate (35ug/lane). SETDB1(arrow) was detected using the purified Pab. |
 | Western blot analysis of SETDB1(arrow) using rabbit polyclonal SETDB1 Antibody (C-term) (Cat# 102-10782). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SETDB1 gene (Lane 2) (Origene Technologies). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.