Rabbit Anti-Human SOCS6 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O14544 |
| Gene Id | 9306 |
| Gene Symbols | SOCS6 |
| Protein Name / Synonyms | SOCS6 (N-term) |
| Clonality | Polyclonal |
| Preparation | This SOCS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human SOCS6. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
Specificity
Other Names
SOCS6; CIS4; SOCS4; Suppressor of cytokine signaling 6; Cytokine-inducible SH2 protein 4; Suppressor of cytokine signaling 4
NCBI Accession #
NP_004223.2
Other Accession #
NP_004223.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
59528
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | SOCS6 Antibody (N-term) (Cat# 102-12320) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SOCS6 antibody detected the SOCS6 protein (arrow). |
 | SOCS6 Antibody (N-term) (102-12320)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SOCS6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.
