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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q15788 |
| Gene Id | 8648 |
| Gene Symbols | NCOA1 |
| Protein Name / Synonyms | SRC1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This SRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-214 amino acids from the N-terminal region of human SRC1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
SRC1 acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. This protein binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion.
Specificity
Predicted Reactivity
Pig
Other Names
NCOA1; BHLHE74; SRC1; Nuclear receptor coactivator 1; Class E basic helix-loop-helix protein 74; Protein Hin-2; RIP160; Renal carcinoma antigen NY-REN-52; Steroid receptor coactivator 1
NCBI Accession #
NP_003734.3;NP_671756.1;NP_671766.1
Other Accession #
Q4PJW2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
156757
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of SRC1 (arrow) using rabbit polyclonal SRC1 Antibody (N-term) (Cat# 102-17424). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SRC1 gene (Lane 2) (Origene Technologies). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.