Rabbit Anti-Human STAT2 (C-term) Antibody, 400 ul
Loading...
Loading...
Loading...
Loading...
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P52630 |
| Gene Id | 6773 |
| Gene Symbols | STAT2 |
| Protein Name / Synonyms | STAT2 (C-term) |
| Clonality | Polyclonal |
| Preparation | This STAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 820-851 amino acids from the C-terminal region of human STAT2. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.
Specificity
Other Names
STAT2; Signal transducer and activator of transcription 2; p113
NCBI Accession #
NP_005410.1;NP_938146.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
97916
Recommended Dilutions
IHC: 1:50-100; WB: 1:1000
 | STAT2 Antibody (C-term) (Cat# 102-12782) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the STAT2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | Western blot analysis of STAT2 Antibody (C-term) (Cat# 102-12782) in K562 cell line lysates (35ug/lane). STAT2(arrow) was detected using the purified Pab. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.