Rabbit Anti-Human TAU (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P10636 |
| Gene Id | 4137 |
| Gene Symbols | MAPT |
| Protein Name / Synonyms | TAU (C-term) |
| Clonality | Polyclonal |
| Preparation | This TAU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 677-707 amino acids from the C-terminal region of human TAU. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, IF |
| Research Area | Neuroscience, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The microtubule-associated protein tau (MAPT) gene transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations result in several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine
Other Names
MAPT; MAPTL; MTBT1; TAU; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau
NCBI Accession #
NP_001116538.2;NP_001116539.1;NP_001190181.1;NP_005901.2;NP_058518.1;NP_058519.3;NP_058525.1
Other Accession #
P19332; P10637; P29172
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
78928
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; IF: 1:10-50
 | Western blot analysis of TAU(arrow) using rabbit polyclonal TAU Antibody (Cat# 102-14750). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the TAU gene (Lane 2) (Origene Technologies). |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
 | Confocal immunofluorescent analysis of TAU Antibody (C-term)(Cat# 102-14750) with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.