Rabbit Anti-Human TGIF (Center L223) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q15583 |
| Gene Id | 7050 |
| Gene Symbols | TGIF1 |
| Protein Name / Synonyms | TGIF (Center L223) |
| Clonality | Polyclonal |
| Preparation | This TGIF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human TGIF. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
TGIF1 is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.
Specificity
Predicted Reactivity
Mouse, Chicken
Other Names
TGIF1; TGIF; Homeobox protein TGIF1; 5'-TG-3'-interacting factor 1
NCBI Accession #
NP_001265611.1;NP_001265613.1;NP_001265615.1;NP_003235.1;NP_733796.2;NP_775299.1;NP_775300.1;NP_775301.1;NP_775302.1;NP_775303.1;NP_777480.1
Other Accession #
Q8C0Y1; Q9GZN2; P70284; Q90655
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
43013
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of anti-TGIF1 Antibody (Center L223) (RB14109) in Y79 cell line lysates (35ug/lane). TGIF1(arrow) was detected using the purified Pab. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.