Rabbit Anti-Human TRIM23 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P36406 |
| Gene Id | 373 |
| Gene Symbols | TRIM23 |
| Protein Name / Synonyms | TRIM23 (N-term) |
| Clonality | Polyclonal |
| Preparation | This TRIM23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the N-terminal region of human TRIM23. |
| Concentration (lot specific) | 0.410 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
TRIM23; ARD1; ARFD1; RNF46; E3 ubiquitin-protein ligase TRIM23; ADP-ribosylation factor domain-containing protein 1; GTP-binding protein ARD-1; RING finger protein 46; Tripartite motif-containing protein 23
NCBI Accession #
NP_001647.1;NP_150230.1;NP_150231.1
Other Accession #
P36407; Q8BGX0; NP_150230.1; NP_001647.1; NP_150231.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
64067
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | TRIM23 Antibody (N-term) (Cat# 102-12083) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the TRIM23 antibody detected the TRIM23 protein (arrow). |
 | TRIM23 Antibody (N-term) (Cat# 102-12083)immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRIM23 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.