Rabbit Anti-Human TrkC Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q16288 |
| Gene Id | 4916 |
| Gene Symbols | NTRK3 |
| Protein Name / Synonyms | TrkC |
| Clonality | Polyclonal |
| Preparation | This TrkC antibody is generated from rabbits immunized with a his tag recombinant protein of human TrkC. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
TRKC, a member of the insuline receptor subfamily of Tyr protein kinases, is a receptor for neurotrophin-3 (NT-3). Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.
Specificity
Other Names
NTRK3; TRKC; NT-3 growth factor receptor; GP145-TrkC; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase
NCBI Accession #
NP_001012338.1;NP_002521.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
94428
Recommended Dilutions
WB: 1:1000
 | TrkC Antibody (Cat# 102-17560) western blot analysis in U87-MG cell line lysates (35ug/lane).This demonstrates the TrkC antibody detected the TrkC protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.