Rabbit Anti-Human UNC13B (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O14795 |
| Gene Id | 10497 |
| Gene Symbols | UNC13B |
| Protein Name / Synonyms | UNC13B (Center) |
| Clonality | Polyclonal |
| Preparation | This UNC13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1062-1091 amino acids from the Central region of human UNC13B. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
UNC13B plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity).
Specificity
Predicted Reactivity
Mouse
Other Names
UNC13B; UNC13; Protein unc-13 homolog B; Munc13-2
NCBI Accession #
NP_006368.3
Other Accession #
Q9Z1N9
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
180679
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | Western blot analysis of UNC13B Antibody (Center) (Cat# 102-18070) in 293 cell line lysates (35ug/lane). UNC13B (arrow) was detected using the purified Pab. |
 | UNC13B Antibody (Center) (Cat# 102-18070) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.