Rabbit Anti-Human VEGF1 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P15692 |
| Gene Id | 7422 |
| Gene Symbols | VEGFA |
| Protein Name / Synonyms | VEGF1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This VEGF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-95 amino acids from the N-terminal region of human VEGF1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Angiogenesis, Cardiovascular Disease, Vascular Biology |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
VEGF1 is a member of the PDGF/VEGF growth factor family and and is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein are linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in VEGF1 have been associated with proliferative and nonproliferative diabetic retinopathy.
Specificity
Other Names
VEGFA; VEGF; Vascular endothelial growth factor A; Vascular permeability factor
NCBI Accession #
NP_001020537.2;NP_001020538.2;NP_001020539.2;NP_001020540.2;NP_001020541.2;NP_001028928.1;NP_001165093.1;NP_001165094.1;NP_001165095.1;NP_001165096.1;NP_001165097.1;NP_001165098.1;NP_001165099.1;NP_00
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
27042
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of VEGF1 Antibody (N-term) polyclonal antibody(Cat# 102-16729)(arrow). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the VEGF1 gene (Lane 2) (Origene Technologies). Molecular weight of monomeric VEGF1 is 27042 Da; higher observed molecular weight band is consistent with common form of disulfide linked homodimer. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.