Rabbit Anti-MME (C-term)

Rabbit Anti-MME (C-term) Antibody, 400 ul
In stock

Product Description


Size 400 µl
Protein Name / Synonyms MME (C-term)
Accession Number P08473
Gene Symbols MME
Gene Id 4311
Concentration (lot specific) 0.410 mg/ml
Preparation This MME antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 721-747 amino acids from the C-terminal region of human MME.
Host Species Rabbit
Clonality Polyclonal
Species Human, Mouse


This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq].


Other Names
MME; EPN; Neprilysin; Atriopeptidase; Common acute lymphocytic leukemia antigen; Enkephalinase; Neutral endopeptidase 24.11; Skin fibroblast elastase; CD_antigen=CD10
NCBI Accession #
Other Accession #
NP_009218.2; NP_000893.2; NP_009219.2; NP_009220.2


Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
MME Antibody (C-term) (Cat# 102-10589) western blot analysis in LNCaP cell line lysates (35ug/lane).This demonstrates the MME antibody detected the MME protein (arrow).
MME Antibody (C-term) (Cat# 102-10589) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MME Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source



2-8°C (short-term); -20°C (long-term)
12 months from the date of shipment when stored properly.
Write Your Own Review
Your Rating
Submit a more detailed review for this product on Biocompare.com to receive an additional $20 Amazon gift card!

Ask a Question

Display name:
Your location:*