Rabbit Anti-Mouse Casc5 (C-term) Antibody, 400 µl
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | Q66JQ7 |
| Gene Symbols | Knl1 |
| Protein Name / Synonyms | Protein CASC5, Cancer susceptibility candidate gene 5 protein homolog, Kinetochore-null protein 1, Casc5, Knl1 |
| Clonality | Polyclonal |
| Clone | RB40173 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Directly links spindle checkpoint proteins BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore (By similarity).
Other Information
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Antigen Source
Mouse
Images
WB (1:1000)
Mouse Casc5 Antibody (C-term) (Cat. #102-23527) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Casc5 antibody detected the Casc5 protein (arrow).
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.