Rabbit Anti-Mouse DHCR7 (C-term)

Rabbit Anti-Mouse DHCR7 (C-term) Antibody, 400 ul
In stock

Product Description


Size 400 µl
Protein Name / Synonyms DHCR7 (C-term)
Accession Number Q9UBM7
Gene Symbols DHCR7
Gene Id 1717
Concentration (lot specific) 0.310 mg/ml
Preparation This DHCR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-463 amino acids from the C-terminal region of human DHCR7.
Host Species Rabbit
Clonality Polyclonal
Species Mouse


This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS); a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by mental retardation, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.


Other Names
DHCR7; D7SR; 7-dehydrocholesterol reductase; Putative sterol reductase SR-2; Sterol Delta(7)-reductase
NCBI Accession #
Other Accession #
NP_001157289.1; NP_001351.2


Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; IF: 1:10-50
DHCR7 Antibody (C-term) (Cat# 102-11101) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the DHCR7 antibody detected the DHCR7 protein (arrow).
DHCR7 Antibody (C-term) (Cat# 102-11101)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DHCR7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Confocal immunofluorescent analysis of DHCR7 Antibody (C-term)(Cat# 102-11101) with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).

Antigen Source



2-8°C (short-term); -20°C (long-term)
12 months from the date of shipment when stored properly.
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