Rabbit Anti-Mouse DTNA (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | Q9Y4J8 |
| Gene Id | 1837 |
| Gene Symbols | DTNA |
| Protein Name / Synonyms | DTNA (C-term) |
| Clonality | Polyclonal |
| Preparation | This DTNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-721 amino acids from the C-terminal region of human DTNA. |
| Concentration (lot specific) | 0.380 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, IF |
| Research Area | Cardiovascular Disease, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Specificity
Other Names
DTNA; DRP3; Dystrobrevin alpha; Alpha-dystrobrevin; Dystrophin-related protein 3
NCBI Accession #
NP_001121647.1;NP_001185867.1;NP_001185868.1;NP_001185869.1;NP_001185871.1;NP_001185873.1;NP_001185874.1;NP_001381.2;NP_001382.2;NP_001383.2;NP_116757.2;NP_116760.2;NP_116761.2;NP_116762.2;NP_116763.1
Other Accession #
NP_116760.2; NP_001383.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
83901
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; IF: 1:10-50
 | DTNA Antibody (C-term) (Cat# 102-11635) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the DTNA antibody detected the DTNA protein (arrow). |
 | DTNA Antibody (C-term) (Cat# 102-11635)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DTNA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | Confocal immunofluorescent analysis of DTNA Antibody (C-term) (Cat# 102-11635) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.