Rabbit Anti-Mouse Irak1 (Center) Antibody, 400 µl
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | Q62406|NP_001171447.1|NP_032389.2 |
| Gene Id | 16179 |
| Gene Symbols | Irak1 |
| Protein Name / Synonyms | Interleukin-1 receptor-associated kinase 1, IRAK, IRAK-1, Pelle-like protein kinase, mPLK, Irak1, Il1rak |
| Clonality | Polyclonal |
| Clone | RB34794 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting, FC |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Irak1 binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. The kinase activity of this enzyme may not be required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1.
Other Information
NCBI Accession #
NP_001171445.1;NP_001171447.1;NP_032389.2
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
77269
Antigen Source
Mouse
Images
WB (1:1000)
Mouse Irak1 Antibody (Center) (Cat. #102-21869) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the Irak1 antibody detected the Irak1 protein (arrow).
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.