Rabbit Anti-Mouse Mavs (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | Q8VCF0 |
| Gene Id | 228607 |
| Gene Symbols | MAVS |
| Protein Name / Synonyms | Mavs (N-term) |
| Clonality | Polyclonal |
| Preparation | This Mouse Mavs antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Mavs. |
| Concentration (lot specific) | 0.350 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease, Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).
Specificity
Other Names
Mavs; Ips1; Visa; Mitochondrial antiviral-signaling protein; CARD adapter inducing interferon beta; Interferon beta promoter stimulator protein 1; Virus-induced-signaling adapter
NCBI Accession #
NP_001193314.1;NP_659137.1
Other Accession #
NP_659137.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
53399
Recommended Dilutions
WB: 1:1000
 | MOUSE Mavs Antibody (N-term) (Cat# 102-14539) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the MOUSE Mavs antibody detected the MOUSE Mavs protein (arrow). |
Antigen Source
MOUSE
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.