OLR1 Polyclonal Antibody
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Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | P78380 |
| Gene Id | 4973 |
| Gene Symbols | OLR1 |
| Protein Name / Synonyms | OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1, oxidized low-density lipoprotein receptor 1 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Background
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
Dilutions
WB 1:500 - 1:1000
Format
Calculated MW
20kDa/21kDa/30kDa
Observed MW
31kDa
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human OLR1 (NP_002534.1).
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of mouse lung, using OLR1 antibody (144-012060) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.
Expiration:
12 months from the date of shipment when stored properly.