Rabbit Anti-Mouse p21Cip1 (C-term S148) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | P39689 |
| Gene Id | 12575 |
| Gene Symbols | CDKN1A |
| Protein Name / Synonyms | p21Cip1 (C-term S148) |
| Clonality | Polyclonal |
| Preparation | This Mouse p21Cip1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-154 amino acids from the C-terminal region of mouse p21Cip1. |
| Concentration (lot specific) | 0.500 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity).
Specificity
Other Names
Cdkn1a;Cip1; Waf1; Cyclin-dependent kinase inhibitor 1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Cyclin-dependent kinase inhibitor 1; Melanoma differentiation-associated protein; Cyclin-dependent kinase inhibitor 1; p21
NCBI Accession #
NP_001104569.1;NP_031695.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
17785
Recommended Dilutions
WB: 1:1000
 | Mouse p21Cip1 Antibody (C-term S148) (Cat# 102-14759) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Mouse p21Cip1 antibody detected the Mouse p21Cip1 protein (arrow). |
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.