Rabbit Anti-MUTED (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q8TDH9 |
| Gene Id | 63915 |
| Gene Symbols | BLOC1S5 |
| Protein Name / Synonyms | MUTED (Center) |
| Clonality | Polyclonal |
| Preparation | This MUTED antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the Central region of human MUTED. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.
Specificity
Predicted Reactivity
Pig
Other Names
MUTED; Protein Muted homolog
NCBI Accession #
NP_001186251.1;NP_958437.1
Other Accession #
A5A777; NP_958437.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
21609
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | MUTED Antibody (Center) (Cat# 102-10562) western blot analysis in MDA-MB435 cell line lysates (15ug/lane).This demonstrates the MUTED antibody detected MUTED protein (arrow). |
 | MUTED Antibody (Center) (Cat# 102-10562) western blot analysis in mouse bladder tissue lysates (15ug/lane).This demonstrates the MUTED antibody detected MUTED protein (arrow). |
 | MUTED Antibody (Center) (Cat# 102-10562) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MUTED Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.