Rabbit Anti-NEDD4L (Center) Antibody, 400 µl
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | Q96PU5|Q8CFI0|NP_001138436.1|NP_001138442.1|NP_001138439.1 |
| Gene Id | 23327 |
| Gene Symbols | NEDD4L |
| Protein Name / Synonyms | E3 ubiquitin-protein ligase NEDD4-like, 632-, NEDD42, Nedd4-2, NEDD4L, KIAA0439, NEDL3 |
| Clonality | Polyclonal |
| Clone | RB34399 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK.
Other Information
NCBI Accession #
NP_001138436.1;NP_001138437.1;NP_001138438.1;NP_001138439.1;NP_001138440.1;NP_001138441.1;NP_001138442.1;NP_001138443.1;NP_001230889.1;NP_056092.2
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
111932
Antigen Source
Human
Images
WB (1:1000)
NEDD4L Antibody (Center) (Cat. #102-22096) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the NEDD4L antibody detected the NEDD4L protein (arrow).
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.