Rabbit Anti-NeuroD1 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | Q13562 |
| Gene Id | 4760 |
| Gene Symbols | NEUROD1 |
| Protein Name / Synonyms | NeuroD1 (C-term) |
| Clonality | Polyclonal |
| Preparation | This NeuroD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-348 amino acids from the C-terminal region of human NeuroD1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Neuroscience |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.
Specificity
Other Names
NEUROD1; BHLHA3; NEUROD; Neurogenic differentiation factor 1; Class A basic helix-loop-helix protein 3
NCBI Accession #
NP_002491.2
Other Accession #
Q64289; Q60867
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
39920
Recommended Dilutions
WB: 1:1000
 | NeuroD1 Antibody (I333) (Cat# 102-14598) western blot analysis in Y79 cell line ,mouse cerebellum and rat brain tissue lysates (35ug/lane).This demonstrates the NeuroD1 antibody detected the NeuroD1 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.