Rabbit Anti-Neurogenin3 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q9Y4Z2 |
| Gene Id | 50674 |
| Gene Symbols | NEUROG3 |
| Protein Name / Synonyms | Neurogenin3 (N-term) |
| Clonality | Polyclonal |
| Preparation | This Neurogenin3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human Neurogenin3. |
| Concentration (lot specific) | 1.900 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, IF |
| Research Area | Neuroscience |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Neurogenin-3 belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm. Neurogenin-3 also required for the specification of a common precursor of the 4 pancreatic endocrine cell types. Defects in NEUROG3 are the cause of congenital malabsorptive diarrhea 4 (DIAR4). DIAR4 is an autosomal recessive disorder characterized by generalized malabsorption and a paucity of enteroendocrine cells.
Specificity
Other Names
NEUROG3; ATOH5; BHLHA7; NGN3; Neurogenin-3; Class A basic helix-loop-helix protein 7; Protein atonal homolog 5
NCBI Accession #
NP_066279.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
23077
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; IF: 1:10-50
 | The Neurogenin3 (N-term) polyclonal antibody (Cat# 102-14610) is used in Western blot to detect Neurogenin3 in mouse liver tissue lysate. |
 | Neurogenin3 Antibody (N-term) (Cat# 102-14610) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the Neurogenin3 antibody detected the Neurogenin3 protein (arrow). |
 | Western blot analysis of Neurogenin3 (arrow) using rabbit polyclonal Neurogenin3 Antibody (N-term) (Cat# 102-14610). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Neurogenin3 gene. |
 | Neurogenin3 Antibody (N-term) (Cat# 102-14610) immunohistochemistry analysis in formalin fixed and paraffin embedded human large intestine followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the Neurogenin3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | Confocal immunofluorescent analysis of Neurogenin3 Antibody (N-term) (Cat# 102-14610) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.