Rabbit Anti-NIP1 (BH3 Domain Specific) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q12981 |
| Gene Id | 662 |
| Gene Symbols | BNIP1 |
| Protein Name / Synonyms | NIP1 (BH3 Domain Specific) |
| Clonality | Polyclonal |
| Preparation | This NIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-127 amino acids from human NIP1. |
| Concentration (lot specific) | 1.930 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Apoptosis |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
NIP1 (BNIP1) is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. Alternative splicing of this gene results in four products of unknown function. Transcript variant BNIP1 contains the entire coding region of the gene. This variant contains a fully conserved BH3 domain, which has been associated with pro-apoptotic function.
Specificity
Other Names
BNIP1; NIP1; SEC20L; Vesicle transport protein SEC20; BCL2/adenovirus E1B 19 kDa protein-interacting protein 1; Transformation-related gene 8 protein
NCBI Accession #
NP_001196.2;NP_053581.2;NP_053582.2;NP_053583.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
26132
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of anti-NIP1 BH3 Domain Pab (Cat# AP1335a) in HL60 cell lysates (35ug/lane). NIP1 BH3 Domain (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.