NPC2 Polyclonal Antibody
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Product Description
Specifications
| Size | 20 µL, 100 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | P61916 |
| Gene Id | 10577 |
| Gene Symbols | NPC2 |
| Protein Name / Synonyms | NPC2, EDDM1, HE1, epididymal secretory protein E1 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.05% proclin300, 50% glycerol, pH 7.3 |
| Recommended Applications | Western Blotting, IHC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Background
This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.
Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IHC 1:50 - 1:200
Format
Calculated MW
13kDa/16kDa
Observed MW
19kDa
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-151 of human NPC2 (NP_006423.1).
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of mouse lung, using NPC2 antibody (144-05413) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
Immunohistochemistry of paraffin-embedded human lung injury using NPC2 Antibody (144-05413) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver injury using NPC2 Antibody (144-05413) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human colon using NPC2 Antibody (144-05413) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human prostate using NPC2 Antibody (144-05413) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human esophagus using NPC2 Antibody (144-05413) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse lung using NPC2 Antibody (144-05413) at dilution of 1:100 (40x lens).
Expiration:
12 months from the date of shipment when stored properly.