Rabbit Anti-OPRM1 (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P35372 |
| Gene Id | 4988 |
| Gene Symbols | OPRM1 |
| Protein Name / Synonyms | OPRM1 (Center) |
| Clonality | Polyclonal |
| Preparation | This OPRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-187 amino acids from the Central region of human OPRM1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
OPRM1 is the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin (see POMC, MIM 176830) and the enkephalins (see PENK, MIM 131330). The OPRM1 receptor is a membrane of the G protein-coupled receptor family (Bond et al., 1998 [PubMed 9689128]). There are at least 3 types of opioid receptors, mu, kappa (OPRK1; MIM 165196), and delta, each with a distinct pharmacologic profile.
Specificity
Predicted Reactivity
Rat, Pig, Monkey
Other Names
OPRM1; MOR1; Mu-type opioid receptor; Mu opiate receptor; Mu opioid receptor
NCBI Accession #
NP_000905.3;NP_001008503.2;NP_001008504.2;NP_001008505.2;NP_001138751.1;NP_001138752.1;NP_001138753.1;NP_001138754.1;NP_001138755.1;NP_001138756.1;NP_001138757.1;NP_001138758.1;NP_001138759.1
Other Accession #
P33535; Q95247; P42866; Q95M54
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
44779
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50; FC: 1:10-50
 | Western blot analysis of OPRM1 Antibody (Center) (Cat# 102-18156) in mouse heart tissue lysates (35ug/lane). OPRM1 (arrow) was detected using the purified Pab. |
 | OPRM1 Antibody (Center) (102-18156)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OPRM1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | OPRM1 Antibody (Center) (Cat# 102-18156) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.