Rabbit Anti-P2RX7 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q99572 |
| Gene Id | 5027 |
| Gene Symbols | P2RX7 |
| Protein Name / Synonyms | P2RX7 (C-term) |
| Clonality | Polyclonal |
| Preparation | This P2RX7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 563-592 amino acids from the C-terminal region of human P2RX7. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.
Specificity
Other Names
P2RX7; P2X purinoceptor 7; ATP receptor; P2Z receptor; Purinergic receptor
NCBI Accession #
NP_002553.3
Other Accession #
NP_002553.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
68585
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | P2RX7 Antibody (C-term) (Cat# 102-16555) western blot analysis in MDA-MB435 cell line and mouse kidney tissue lysates (15ug/lane).This demonstrates the P2RX7 antibody detected the P2RX7 protein (arrow). |
 | P2RX7 Antibody (C-term) (Cat# 102-16555) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the P2RX7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.