Rabbit Anti-PGAM2 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P15259 |
| Gene Id | 5224 |
| Gene Symbols | PGAM2 |
| Protein Name / Synonyms | PGAM2 (N-term) |
| Clonality | Polyclonal |
| Preparation | This PGAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-41 amino acids from the N-terminal region of human PGAM2. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). PGAM2 encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X.
Specificity
Other Names
PGAM2; PGAMM; Phosphoglycerate mutase 2; BPG-dependent PGAM 2; Muscle-specific phosphoglycerate mutase; Phosphoglycerate mutase isozyme M
NCBI Accession #
NP_000281.2
Other Accession #
NP_000281.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
28766
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | PGAM2 Antibody (N-term) (Cat# 102-10676) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the PGAM2 antibody detected the PGAM2 protein (arrow). |
 | PGAM2 Antibody (N-term) (Cat# 102-10676) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the PGAM2 antibody detected the PGAM2 protein (arrow). |
 | PGAM2 antibody (N-term) (Cat# 102-10676) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PGAM2 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.