Anti-Phospho-ALOX5-S271 Antibody

Phospho-ALOX5-S271 Polyclonal Antibody
As low as $211.00
In stock
Only %1 left

Product Description


Size 50 ul, 100 ul, 200 ul
Species Human
Host Species Rabbit
Isotype Igg
Buffers 50% glycerol, PBS with 0.02% sodium azide, pH7.3.
Protein Name / Synonyms ALOX5, 5-LO, 5-LOX, 5LPG, LOG5, arachidonate 5-lipoxygenase
Accession Number P09917
Gene Symbols ALOX5
Gene Id 240
Purity Affinity purification


This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.


WB 1:500 - 1:2000


Calculated MW
Observed MW


A phospho specific peptide corresponding to residues surrounding S271 of human ALOX5


Phospho S271




Western blot analysis of extracts of HT-29 cells, using Phospho-ALOX5-S271 antibody (144-50573) at 1:1000 dilution. HT-29 cells were treated by PMA/TPA (200nM).
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% BSA.
Western blot - Phospho-ALOX5-S271 antibody (144-50573)

12 months from the date of shipment when stored properly.
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